Trilateral Retinoblastoma: a Literature
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چکیده
This study analyzes modern views on the history, variants, age at diagnosis of trilateral retinoblastoma, median time from retinoblastoma to trilateral retinoblastoma, the largest size and percentage of trilateral retinoblastoma among retinoblastoma cases, functions of pineal gland, genetics, ocular and intracranial histology, diagnosis, treatment, therapy results, survival rates and frequency of screening of trilateral retinoblastoma.
منابع مشابه
The Incidence of Trilateral Retinoblastoma: A Systematic Review and Meta-Analysis.
PURPOSE To estimate the incidence of trilateral retinoblastoma in patients with retinoblastoma. DESIGN Systematic review and meta-analysis. METHODS We searched Medline and Embase for scientific literature published between January 1966 and July 2015 that assessed trilateral retinoblastoma incidence. We used a random-effects model for the statistical analyses. RESULTS We included 23 retino...
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BACKGROUND About 5% of children with retinoblastoma from germline mutation of the RB1 gene are at risk of developing trilateral retinoblastoma--intraocular retinoblastoma combined with a histologically similar brain tumour, most commonly in the pineal gland. We aimed to provide a systematic overview of published data for trilateral retinoblastoma, and to analyse how survival has changed. METH...
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Two cases of trilateral retinoblastoma (a syndrome of midline, undifferentiated, intracranial tumor in a child with hereditary, bilateral ocular retinoblastoma) are described, one with a unique location of the intracranial tumor, and the other with an unusual temporal course of disease.
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Trilateral retinoblastoma is a rare, but well recognized syndrome. These tumors usually occur in the pineal, parasellar, or suprasellar regions several years after successful management of ocular retinoblastomas without evidence of direct extension or distant metastasis. Here we report a case of trilateral retinoblastoma presenting initially with a sellar tumor and with concurrent unilateral re...
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